Applications

Biomolecular Interaction Analysis - Creoptix™ WAVEsystem

Real Samples, Real Data

Kinetic data is the foundation for assessing molecular and protein interactions, so shouldn’t that data be as accurate and relevant as possible?

Study protein interactions in real time

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Kinetics: it's all in the curvature

The Creoptix™ WAVEsystem allows you to confidently detect and quantify biological interactions in real-time, providing you with both binding affinity and kinetics. An interaction between two species (a protein and a small molecule, for example) is displayed as a graph, referred to as a sensorgram, showing binding response vs. time. Though the signal level in a sensorgram correlates to the species involved and the strength of their interaction, it’s in the curvature of its association and dissociation phases where the valuable information resides. So is, for example, the desired biological effect of a drug linked to its residence time (dissociation phase) rather than to its affinity only.

Experience real kinetics with the WAVEsystem

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Small Molecules

Separate binders from non-binders

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Membrane Proteins

Kinetics while retaining conformation and activity

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Serology

Binding kinetics in conditions closer to real life

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Biologics

Confirm and validate ELISA data

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COVID-19 Research

Generate novel data to strengthen publications

  • Real Samples, Real Data

    The Creoptix™ WAVEsystem

    Confidently detect and quantify biological interactions in real-time, for high-quality kinetic data across a broader range of samples than traditional equipment.

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