Events

SWEPROT 2021 is a virtual conference mixing scientific presentations in 2D video conference format with Virtual Reality (VR) sessions for poster presentations, Q&A and games. The conference starts Sunday June 20^th late afternoon with a visualization keynote lecture, introducing registered participants to the VR environment of SWEPROT 2021. Monday and Tuesday includes the main scientific program, five keynote lectures, short presentations by young scientists selected from submitted abstracts, poster sessions, sponsor exhibition, question and answer sessions as well as games and evening activities.

Creoptix is an official sponsor of the virtual conference and will be present with a virtual poster.

In drug discovery, selection of compound hits with a potential for further development requires a full characterization of binding kinetics. Biophysical techniques such as isothermal titration calorimetry (ITC) and Grating-Coupled Interferometry (GCI) provide information on the global binding mechanisms of protein-protein or protein-ligand interaction, essential for hit characterization.

In the first part of the webinar, May Poh Lay, Senior Applications Specialist at Creoptix, will explain why the measurement of kinetics is critical when screening molecules, outlining the GCI technology behind WAVEsystem, how you can use the system, and the associated benefits.

In the second part, Dr. Calliste (Reiling) Scholl, Application Engineer at TA Instruments, will talk about Isothermal Titration Calorimetry (ITC) and how binding interactions driven by enthalpic contributions are more specific, leading to less off-target binding resulting in fewer side effects.

Register now and find out more about Binding Interaction Workflow Solutions.

Are you interested to learn more about hit identification in Fragment Based Drug Discovery?

Join us at 'Discovery Week: Online' on June 3rd organized by Oxford Global Conferences for a Thought Leadership Session with Professor Helena Danielson from Uppsala University. Helena will talk about how fragment kinetics can be resolved, how extraction of essential information depends on appropriate experimental design, and how novel biosensor technologies provide new possibilities for Drug Discovery.

Being able to test newly synthesized molecules is a pivotal part of early-stage drug discovery, with the data from assays driving decisions on the next molecules to be developed. The waveRAPID technology enables testing of full kinetic parameters for up to 400 compound fragments unattended in a 24-hour period.

Trevor Askwith presents how Domainex is using waveRAPID to accelerate the analogue expansion to support our fragment and virtual screening hit ID platforms.

Kinetics expert, Dr. Thomas Schubert will present how using the model system P38 to demonstrate a screening application of waveRAPID, using a library of kinase inhibitors. With waveRAPID®, 2bind is now able to efficiently screen 1000s of molecules for binding kinetics and affinity.

Kinetics in hours instead of days

Introducing the waveRAPID^®, the new way of measuring kinetics to boost throughput. Instead of relying a titration series in conventional kinetics, waveRAPID injects a single concentration, pulsing the sample over the sensing surface at increasing durations. From a single well, kinetics can be derived: the on-rate, off-rate, affinity and R_max. With no need for serial dilutions or DMSO corrections, set-up time is significantly reduced, runs are faster, and wells are freed up to run more samples.

We have put together a fantastic line-up of scientists from both industry in academia to share their experiences with the waveRAPID.

Very excited to be part of the SLASDigital 2021 Conference again this year. Don't miss the chance to visit our virtual booth, interact with our team for a sneak peak at waveRAPID^® and keep an eye on the New Product Award announcement on January 27th!

In this seminar we want to get your feedback on our brand new product – waveRAPID^® – which stands for Rapid Analyte Pulses of Increasing Duration. With this new way of measuring kinetics, short pulses of increasing duration – but same concentration – are used to probe biomolecular interactions. Be ready to obtain a complete kinetic readout (including on- and off-rates) from a single well and WAVE goodbye to serial dilutions and DMSO corrections.

Discover the benefits of early stage kinetic characterization to complement and validate binding affinity in crude reaction mixtures, biofluids (serum and plasma) and other matrixes with Dr. Michael Goldflam (Pepscan) and Dr. Fabio Andres (Creoptix).

Discover the benefits of early stage kinetic characterization with our WAVEsystem at PEGSVirtual 2020. Expect to see high-quality kinetics in a wide range of crude samples ranging from peptides to membrane proteins and relevant clinical samples.

Discover the WAVEsystem in less than 30 minutes with out Let's Talk Kinetics! Virtual Seminar Series. Get acquainted with our GCI technology and the applications of our WAVEsystem for small molecule research and binding kinetics onto membrane proteins.

In this webinar, Dr. Shawn Owen (University of Utah) discusses advanced characterization techniques to assess antibody-drug conjugates (ADCs), while Dr. Ellen Lee (Creoptix), goes deep into the biophysical characterization of biologics using the Creoptix WAVEsystem.

Experience a new level of performance and flexibility in drug discovery with our CTO and Founder Kaspar Cottier at the Hellen Diller Auditorium @UCSF, Mission Bay in San Francisco. In a nutshell, sensorgrams galore!