Binding Kinetics Supporting Peptide Discovery
Webinar
We’ve joined forces with Dr. Michael Goldflam from Pepscan to deliver a webinar full of peptides and kinetic characterization for therapeutic and diagnostics development.
Why this webinar?
CLIPS® meets the WAVE
In this webinar, Dr. Michael Goldflam (Pepscan) will present the CLIPS® discovery pipeline for the development of peptides for therapeutic and diagnostic purposes starting from phage encoded constrained peptide libraries to the optimization of lead compounds. Dr. Fabio Andres (Creoptix), goes deep into the biophysical characterization of molecules using the Creoptix® WAVEsystem for label-free, real-time affinity and kinetics characterization. Discover the benefits of early stage kinetic characterization to complement and validate binding affinity in crude reaction mixtures, biofluids (serum and plasma) and other matrixes.
What can I expect to learn during this webinar?
- Optimization of peptides for therapeutic and diagnostic purposes.
- Off-rate screening as a valuable alternative approach to small molecule fragments and peptide selection in drug discovery.
- GCI technology can be used as orthogonal validation technique for ELISA data.
- Measuring kinetics in biofluids provides valuable insights into a drug’s efficacy.
- CLIPS® as a powerful and bio-orthogonal peptide cross linking chemistry.
- Identification of CLIPS® constrained redox-stable macrocyclic peptides via phage display and NGS analysis.