The binding kinetics of several approved drugs Danusertib, among others to Aurora A Kinase were recently studied by the lab of Dr. Dorothee Kern at Brandeis University. The group published the results in the open access journal e-Life. (Danusertib, among others)
The Creoptix WAVE system helps reveal new insights in brassinosteroid signalling. The results, obtained by Prof. Michael Hothorn’s group at the University of Geneva, were recently published in Nature Plants.
Prof. Michael Hothorn’s group at the University of Geneva studied the activation of plant membrane receptor kinases with the Creoptix WAVE system. Read all about it in this open access PNAS paper.
Creoptix announces entering UK market with Mologic as first customer and providing new research avenues for Mologic’s Centre for Advanced Rapid Diagnostics (“CARD”) Press Release
We are hiring sales representatives for Europe and the US.
In order to strengthen our sales efforts and our customer support, Creoptix is hiring a Field Application Scientist for the US Territory. Please find the profile here: Field Application Scientist – US Territory
In order to strengthen our sales efforts, Creoptix is seeking a Sales Manager North America. Please find the profile here: Sales Manager North America
Small Molecules can't hide anymore...not even behind large drug targets! Thanks to Novartis for providing the material, our new TechNote shows how Creoptix WAVE pushes the limits regarding sensitivity: Kinetics of a 300Da small molecule with a 110 kDa drug target at Rmax below 1 pg/mm2! Tech Note
Creoptix proudly announces three new Tech Notes demonstrating the benefits of the Creoptix™ WAVE system for molecular interaction analysis:
Fast Off-Rates: Based on very fast injection processes, the Creoptix™ WAVE enables reliable analysis of off-rates of 5 per second! This now allows for off-rate screening and ranking of weak binders such as fragments in a very early discovery process.
Kinetics at High Serum: The innovative disposable microfluidics of the Creoptix™ WAVE provides very high robustness against complex matrices and does not clog at even 100% untreated blood serum. This allows kinetic analysis at much higher serum concentrations than ever before.
Avoiding Mass Transport: Kinetic data quality is significantly impaired by mass transport due to the high immobilization levels required. Thanks to the exceptionally high sensitivity of the Creoptix™ WAVE, reliable kinetics below 1 pg/mm2 are possible and immobilization levels can be markedly reduced. This not only reduces sample consumption but also mass transport limitation.
Creoptix is looking forward to meeting Merck's scientists at the upcoming Merck Technology Symposium taking place on June 2-3, 2015 in Somerset NJ
Creoptix to exhibit at the Drug Discovery Chemistry 2015 in San Diego CA, April 21-23, 2015
Creoptix to exhibit at the Fragments 2015 in Cambridge UK, March 22-24, 2015
Creoptix to exhibit at the Label-Free Technologies Conference in Cambridge MA, March 12-14, 2015
Creoptix proudly announces Dr. Walter Huber as keynote speaker on workshop on March 11 at Swissnex Boston:
Swiss Excellence in Drug Discovery featuring Dr. Walter Huber: "Label-Free Technologies - Overview, Experiences & Perspectives"
Creoptix selected to present at the Late Night with LRIG at the upcoming SLAS2015 in Washington DC. We look forward to seeing you soon in Washinton!
Creoptix to exhibit at the Future Expo during the Eureka Innovation Event and the Swiss Innovation Forum in Basel, Switzerland on November 19 & 20 (Future Expo exhibitor list: DE / ENG)
Creoptix to exhibit at the 10th Annual European Antibody Congress in Geneva, Switzerland on November 10-12, 2014
Creoptix to support the Fragment-based Lead Discovery Conference 2014 in Basel, Switzerland on September 21-24, 2014
Creoptix AG announces carbonic anhydrase data highlighting the exceptional high resolution of the Creoptix™ WAVE system.
Creoptix AG announces the launch of its WAVE system.
We have moved into new facilities, you can now reach us at Einsiedlerstrasse 34, CH-8820 Wädenswil.
Creoptix to support the 15th Annual Drug Discovery Summit in Geneva (press release).