Creoptix® WAVEsystem

Expanding the boundaries in drug discovery

The Creoptix WAVEsystem puts a breakthrough level of kinetics analysis at your fingertips by pushing the boundaries of affinity range and sample compatibility. The system’s exceptionally high data quality, sample compatibility and automated software facilitates drug discovery and enable new inroads into R&D.

Advantages

The Creoptix^® WAVEsystem combines crude sample robustness, high sensitivity, and sophisticated software, to create a novel optical biosensor platform for real-time label-free binding kinetics. Engineered around innovative microfluidics and our proprietary Grating-Coupled Interferometry (GCI) technology, novel data from difficult samples is now possible for unsurpassed insight.

How to benefit:

• Crude samples, harsh chemicals, and particles up to 1000 nm
• Self-contained disposable cartridge and small footprint
• Ultra-fast transition times of 150 ms with reliable determination of off-rates up to 10 s^-1
• Superior signal-to-noise ratios (0.01 pg/mm² at 1 Hz)
• Reliable kinetics and binding affinities (K_D) from low pM to low mM with from signals below 1 pg/mm²
• Analyze large ligand‑to‑analyte molecular weight ratios up to >1000:1
• Up to 120 hours of unattended operation

Explore the system's components

• Measure interactions, not interference

  WAVEcore®

  Engineered around a proprietary Grating-Coupled Interferometry (GCI) technology, the Creoptix^® WAVE system builds on waveguide interferometry to achieve superior resolution in signal and time. With low limits of detection, the WAVEsystem generates accurate kinetic rates, affinity constants, and concentrations of label-free biomolecular interactions, even at low analyte abundance, with no loss of definition.

  

• A sensor chip for every need

  WAVEchip®

  WAVEchip^®- Innovative design and patented microfluidic cartridge to support crude samples, pathogenic samples, harsh solvents, and large particles up to 1000 nm normally only achieved with plate-based assays for kinetic analysis not possible before

  

• Fast, intuitive, automated

  WAVEcontrol

  Move seamlessly from sample to data in a simple stepwise process, generating outputs at the touch of a button. Benefit from waveRAPID, a novel method implemented on the existing WAVEdelta instruments allowing you to obtain kinetics of an interaction by injections from a single well.

  

• Smooth operations

  WAVEcare

  Our WAVEcare programs offer carefree or basic support for high-quality kinetic data and unparalleled performance. Ensure the continuous, high performance operation of your WAVEsystem by choosing the program that fits your needs.

  

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