A sensor chip for every need
No-clog microfluidic design explained
The innovative design of our patented microfluidic cartridge supports
crude samples, pathogenic samples, harsh solvents, and large particles
up to 1000 nm, enabling reliable kinetic analysis. WAVEchips can be
exchanged within minutes for fresh microfluidics.
Our WAVEchips are compatible with:
- 100% Serum & plasma & cell supernatant
- Non-traditional solvents, including high percentages of acetonitrile and DMSO
- Viscous detergents and additives to solubilize membrane proteins
- Cell membrane preps, partially solubilized, unpurified material
- Virus-like particles (VLPs), liposomes, or nanodiscs used as solubilization structures
- Large binding partners: nanoparticles and crude membrane preps
Innovative, No-Clog Microfluidic Cartridge
The innovative design of our patented microfluidic cartridge supports crude samples, pathogenic samples, harsh solvents, and large particles up to 1000 nm normally only achieved with plate-based assays for kinetic analysis not possible before.
Measure the toughest samples
Maintaining samples in native configuration and physiological conditions reduces the risk of protein inactivation or denaturation, ensuring the raw data generated is a faithful depiction of kinetic activity. However, large particles above 100nm in diameter tend to clog other systems.
By combining the microfluidics and biosensor in a single disposable cartridge, Creoptix WAVE system offers crude-sample robustness normally only achieved with plate-based assays. Compatible sample types include 100% serum or plasma, cell lysates, crude membranes preparations, large drug targets, virus-like particles (VLPs), liposomes, and aggregates (fibrils) without clogging-risk.
The chemical-friendly cartridge also makes it amenable to work with high concentrations of DMSO, acetonitrile, and other organic solvents typical of fragment libraries, and viscous detergents allowing exploration of solubilization and purification conditions for membrane proteins. And because the cartridges are self-contained and disposable, they eliminate cross-contamination protecting your samples and ensuring more reliable data.
No-Clog for Crude Samples
No-clog microfluidics accommodates of a broad range of sample types to preserve activity and biological context, saving time from detrimental purification steps and clogging that takes other systems offline.