waveRAPID® - the new way of measuring kinetics
Speeding up the early stages of drug discovery is crucial to getting new medicines to the patients faster. On the commercial side, accelerating R&D will improve the profitability of new therapies and shorten time-to-revenue. Addressing those needs Creoptix is proud to introduce waveRAPID, the new way of measuring kinetics.
What is waveRAPID?
Instead of relying on a titration series, waveRAPID (Repeated Analyte Pulses of Increasing Duration) injects a single concentration, pulsing the sample over the sensing surface at increasing durations, meaning kinetics can be derived from a single well.
What are the benefits of waveRAPID?
With no need for serial dilutions or DMSO corrections, set-up time is significantly reduced, runs are faster, and wells are freed up to run more samples. In summary, waveRAPID offers the following benefits:
- Save time and costs: more interactions in hours, not days
- Get more insight: capacity to screen broad kinetic range
- Run more samples: transform 96 well plate to 96 datasets
- Ease-of-use: accelerate kinetic screen
Curious? Get the latest TechNote about pushing the boundaries in pharmaceutical hit discovery with waveRAPID.
Expert Webinars: Part I
In this expert webinar, Dr. Kaspar Cottier, CTO and Founder of Creoptix, will explain why the measurement of kinetics is important when screening molecules, outlining the technology behind waveRAPID, how you can use the system, and the associated benefits.
Expert Webinars: Part II
Find out how leadXpro, an emerging lead compound discovery company, uses the WAVEsystem to assist its study of membrane protein structural biology. Dr. Nicolas Bocquet, Senior Scientist at leadXpro, will compare the use of the waveRAPID to classical methods for studying biologics and small molecules and illustrate the benefits of the waveRAPID method using screening examples.
Expert Webinars: Part III
In this webinar, Prof. Helena Danielson, Professor of Biochemistry at Uppsala University in Sweden, will explore how her team uses waveRAPID to resolve fragment kinetics and discuss the associated benefits of the system for drug discovery pipelines.
Voices from the Market
Learn what scientists from both industry and academia think about waveRAPID.
Senior Scientist - leadXpro
Nicolas Bocquet, PhD
“Sensitivity and speed are crucial for our experiments – waveRAPID is six times faster than traditional methods. In addition, waveRAPID offers a new way of measuring kinetics to increase throughput and thus productivity in the laboratory.”
Professor of Biochemistry - University of Uppsala
Helena Danielson, PhD
“The waveRAPID system has given us a novel approach to our experimental work-flow and selection of hits. Being able to select fragments on the basis of a kinetic analysis is an advantage and opens up new opportunities for fragment library screening and characterization.”