Publications

Our Creoptix® WAVEsystem is featured in scientific articles in the following (peer-reviewed) journals

  • Plant Sciences

    24.11.2020

    PNAS, 2020

    A. D. Crook, A. C. Willoughby, O. Hazak, S. Okuda, K. R. VanDerMolen, C. L. Soyars, P. Cattaneo, N. M. Clark, R. Sozzani, M. Hothorn, C. S. Hardtke, Z. L. Nimchuk. “BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots.”

  • Peptides

    24.11.2020

    PNAS, 2020

    A. D. Crook, A. C. Willoughby, O. Hazak, S. Okuda, K. R. VanDerMolen, C. L. Soyars, P. Cattaneo, N. M. Clark, R. Sozzani, M. Hothorn, C. S. Hardtke, Z. L. Nimchuk. “BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots.”

  • COVID-19 Research

    24.11.2020

    bioRxiv, 2020

    J. D. Walter, C. A. J. Hutter, A. A. Garaeva, M. Scherer, I. Zimmermann, M. Wyss, J. Rheinberger, Y. Ruedin, J. C. Earp, P. Egloff, M. Sorgenfrei, L. Hürlimann, I. Gonda, G. Meier, S. Remm, S. Thavarasah, G. Zimmer, D. J. Slotboom, C. Paulino, P. Plattet, M. A. Seeger. “Highly potent bispecific sybodies neutralize SARS-CoV-2.”

  • Biologics Development

    24.11.2020

    bioRxiv, 2020

    J. D. Walter, C. A. J. Hutter, A. A. Garaeva, M. Scherer, I. Zimmermann, M. Wyss, J. Rheinberger, Y. Ruedin, J. C. Earp, P. Egloff, M. Sorgenfrei, L. Hürlimann, I. Gonda, G. Meier, S. Remm, S. Thavarasah, G. Zimmer, D. J. Slotboom, C. Paulino, P. Plattet, M. A. Seeger. “Highly potent bispecific sybodies neutralize SARS-CoV-2.”

  • Biologics Development

    24.11.2020

    bioRxiv, 2020

    J. D. Walter, C. A. .J. Hutter, I. Zimmermann, M. Wyss, P. Egloff, M. Sorgenfrei, L. M. Hürlimann, I. Gonda, G. Meier, S. Remm, S. Thavarasah, P. Plattet, M. A. Seeger. “Sybodies targeting the SARS-CoV-2 receptor-binding domain.”

  • COVID-19 Research

    24.11.2020

    bioRxiv, 2020

    J. D. Walter, C. A. .J. Hutter, I. Zimmermann, M. Wyss, P. Egloff, M. Sorgenfrei, L. M. Hürlimann, I. Gonda, G. Meier, S. Remm, S. Thavarasah, P. Plattet, M. A. Seeger. “Sybodies targeting the SARS-CoV-2 receptor-binding domain.”

  • Plant Sciences

    24.11.2020

    Plant Physiology, 2020

    P. Jimenez Sandoval, J. Santiago. “In vitro analytical approaches to study plant ligand-receptor interactions.”

  • Plant Sciences

    24.11.2020

    PNAS, 2020

    S. Moussu, C. Broyart, G. Santos-Fernandez, S. Augustin, S. Wehrle, U. Grossniklaus, J. Santiago. "Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth."

  • Peptides

    24.11.2020

    PNAS, 2020

    S. Moussu, C. Broyart, G. Santos-Fernandez, S. Augustin, S. Wehrle, U. Grossniklaus, J. Santiago. "Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth."

  • Plant Sciences

    24.11.2020

    Science, 2020

    N. M. Doll, S. Royek, S. Fujita, S. Okuda, S. Chamot, A. Stintzi, T. Widiez, M. Hothorn, A. Schaller, N. Geldner. "A two-way molecular dialogue between embryo and endosperm is required for seed development."

  • Plant Sciences

    24.11.2020

    PNAS, 2020

    S. Okuda, S. Fujita, A. Moretti, U. Hohmann, V.G. Doblas, Y. Ma, A. Pfister, B. Brandt, N. Geldner, M. Hothorn. "Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2."

  • Peptides

    24.11.2020

    PNAS, 2020

    S. Okuda, S. Fujita, A. Moretti, U. Hohmann, V.G. Doblas, Y. Ma, A. Pfister, B. Brandt, N. Geldner, M. Hothorn. "Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2."

  • Protein-Protein Interactions

    24.11.2020

    Analyst, 2019

    B. Peter, A. Saftics, B. Kovacs, S. Kurunczi, R. Horvath. "Oxidation increases the binding of EGCG to serum albumin revealed by kinetic data from label-free optical biosensor with reference channel."

  • Plant Sciences

    24.11.2020

    The EMBO Journal, 2019

    K. Lau, R. Podolec, R. Chappuis, R. Ulm, M. Hothorn. "Plant photoreceptors and their signaling components compete for binding to the ubiquitin ligase COP1 using their VP-peptide motifs."

  • Peptides

    24.11.2020

    The EMBO Journal, 2019

    K. Lau, R. Podolec, R. Chappuis, R. Ulm, M. Hothorn. "Plant photoreceptors and their signaling components compete for binding to the ubiquitin ligase COP1 using their VP-peptide motifs."

  • Biologics Development

    24.11.2020

    Journal of Molecular Biology, 2019

    F. Andres, L. Iamele, T. Meyer, J.C. Stüber, F. Kast, E. Gherardi, H.H. Niemann, A. Plückthun. "Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking."

  • Plant Sciences

    24.11.2020

    Life Science Alliance Journal, 2019

    L. Lorenzo-Orts, U. Hohmann, J. Zhu, M. Hothorn. "Molecular characterization of CHAD domains as inorganic polyphosphate-binding modules."

  • Plant Sciences

    24.11.2020

    Nature Plants, 2018

    
U. Hohmann, J. Nicolet, A. Moretti, L.A. Hothorn, M. Hothorn, "The SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signalling."

  • Plant Sciences

    24.11.2020

    PNAS, 2018

    U. Hohmann, J. Santiago, J. Nicolet, V. Olsson, F. Spiga. L.A. Hothorn, M.A. Butenko, M. Hothorn, "Mechanistic basis for the activation of plant membrane receptor kinases by SERK-family coreceptors."

  • Small Molecules/FBDD

    24.11.2020

    E-Life, 2018

    W. Pitsawong, V. Buosi, R. Otten, R.V. Agafonov, A. Zorba, N. Kern, S. Kutter, G. Kern, R.A.P. Pádua, X. Meniche, D. Kern. "Dynamics of human protein kinase Aurora A linked to drug selectivity."

  • Small Molecules/FBDD

    24.11.2020

    Scientific Reports, 2020

    H. Jankovics, B. Kovacs, A. Saftics, T. Gerecsei, E. Tóth, I. Szekacs, F. Vonderviszt, R. Horvath. “Grating-coupled interferometry reveals binding kinetics and affinities of Ni ions to genetically engineered protein layers.”

  • Small Molecules/FBDD

    24.11.2020

    Nature Communications, 2021

    C. Hong, N.J. Byrne, B. Zamlynny, S. Tummala, L. Xiao, J.M. Shipman, A.T. Partridge, C. Minnick, M.J. Breslin, M.T. Rudd, et al. “Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.”

  • Small Molecules/FBDD

    24.11.2020

    RSC Advances, 2021

    E.A. FitzGerald, M.T. Butko, P. Boronat, D. Cederfelt, M. Abramsson, H. Ludviksdottir, J.E. van Muijlwijk-Koezen, I.J.P. de Esch, D. Dobritzsch, T. Young, H. Danielson. “Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor”